The 19-year-old limped off in the second half owing to an injury and Diego Simeone will be praying it's not serious.
It was an up and down day for debutants at the Wanda Metropolitano stadium in the Spanish capital. Getafe striker Jorge Molina was shown a red card in the 38th for a foul from behind on Atletico midfielder Thomas Partey.
It was no more than the home side deserved after a dominant start and they were dealt a further boost when Molina saw his initial yellow card switched to red following a VAR consultation after he caught Thomas Partey's heel with his studs.
Getafe almost pulled off an equalizer a few minutes from the end but Angel Rodriguez's long-range shot hit the crossbar.
The Frenchman used Bale sparingly in the 11 league games he oversaw last season, and in July he said the club were trying to sell the player, even remarking that "the best thing would be if he left tomorrow".
"It seemed that Bale was going to leave but today he is here with us", the French World Cup victor remarked ahead of the start of the new Spanish season. But it is surprising to see Real only have four senior central midfield players in the squad after allowing Marcos Llorente to go to Atletico for around £40m and Dani Ceballos move to Arsenal on loan.
Barcelona have impressed all summer and they have done so without Lionel Messi who is yet to play because of injury - despite their shock 1-0 defeat at Athletic Bilbao in their La Liga opener on Friday.
Despite a poor preseason and some struggles in defense, Real Madrid is expected to be able to contend in the league and possibly be a threat in Europe. He lost his Spain position just before the 2018 World Cup for taking the Madrid job without telling Spanish soccer officials in advance.
A penalty was awarded to Espanyol early in the second half, but the call was reversed after video review.
Madrid endured a hard pre-season campaign, winning only two of seven fixtures and suffering an embarrassing 7-3 defeat to Atletico Madrid, but Zidane said his team were excited about the new campaign.