Truex led the most laps on Saturday, but he had to hold off Joey Logano and Clint Bowyer over the final 50 laps.
"I always looking forward to Richmond", Busch said in a media release. "I had not front turn. It's really cool. As a driver, you wish it could widen out and give you more options of being able to run around in different grooves, but it hasn't shown us that the last couple of years".
"I was able to get to the 19, but it just wasn't enough", he noted. "Being out front was important tonight".
Logano appeared to have a auto capable of taking the victory in his own right for much of the 400-lap race, running Truex down and passing him to win the second stage as he led 52 laps in the middle portion of the event.
Kevin Harvick won the pole for Saturday night's Cup Series race at Richmond Raceway.
"We really closed on the leaders there at the end".
"The consensus at Richmond is, of course, just trying to get your vehicle to turn, but also having really good forward bite", Busch said. Finally it all came together for his 20th career Cup victory.
Harvick was sixth in the first round, second to Kyle Busch in the second round and first with the pole at stake.
Logano held on for second.
Denny Hamlin would love to think he has an advantage when it comes to racing at Richmond Raceway.
"We were close, just not close enough", Logano said. Ran out of time.
"We did a great job today, I didn't think it was a flawless lap from my standpoint, but I was able to get in the throttle on the exit of the corner and put down a decent lap", Harvick said.
"When you're frustrated with second, that's a good sign about where your team's at". TOYOTA OWNERS 400 - to win here in a Toyota was huge.
Busch, seeking his third consecutive victory at Richmond, was followed by Harvick, brother Kurt Busch, Joey Logano and Paul Menard when everyone headed to the pits for fresh tires and fuel.
Joe Gibbs said he can't explain his team's dominant start to the season, but he's going to enjoy it while it lasts. "I could just roll out, and here it doesn't benefit you to wait so you just roll out and get your lap in". "I think that's the reason why you need to enjoy it in pro sports because you know, odds are, this ain't going to keep happening".
NASCAR says eight cars failed prerace inspection, including three that failed twice.
Five other teams failed inspection and had their qualifying speeds and pit selections disallowed. Martin Truex Jr., Chase Elliott, Austin Dillon, Daniel Suarez and Jimmie Johnson earned positions six through 10 on the grid, respectively.