Chelsea continued to push for a second early goal with Loftus-Cheek seeing a low effort from inside the area tipped wide by Denys Boyko, while the goalkeeper also had to react well to keep out Giroud's header.
Giroud, on the other hand, will want to increase his goal tally for the season, and has been in good form in the Europa league, mustering six goals in eight games so far.
"He did very well".
Maurizio Sarri said Olivier Giroud remains a "very important" player for Chelsea after his hat-trick against Dynamo Kiev. "He has been able to train after the problem with the back". He had a wonderful match and I'm really happy that he could play for 90 minutes.
'His potential is very, very high.
"Physically, technically and tactically he is improving, he can become one of the best midfielders not only in England but in Europe".
The NSC Olympic Stadium hosted last season's UEFA Champions League final between Real Madrid and Liverpool, which the Spanish side won 3-1.
Giroud's flawless hat-trick means he is the Europa League's top scorer this season with nine goals and Sarri was delighted with his display.
"First of all, because it means we are in the final and I am happy with that".
"Tonight we've done well at set-pieces, and it's nice because when you can score goals from set-pieces you understand that you can get more points at the end of the championship, and obviously when you play Europa League".
"Firstly, I'd love him to stay at Chelsea", the Derby County boss told talkSPORT.
"We scored after five minutes which was a very hard situation for the opponents".