Switzerland's Bencic, ranked 45th, beat the Czech 6-3 1-6 6-2 to claim her first WTA title since 2015.
Kvitova won in Dubai in 2013 and is playing the event for the first time in three years while 21-year-old Bencic has reached her first final since October in Luxembourg.
By the time she got to Kvitova, who has had a full and rather eventful month that included reaching the Australian Open final and testifying against the man who allegedly attacked her in her apartment, it was nearly fate. As Kvitova double-faulted that gave rise to a set point to Bencic, without wasting any time the Swiss slammed a breathtaking backhand victor and sealed the opening first 6-3.
'We started the week with eight of the top 10 players in the world yet an unseeded player has won the title, reflecting the intense competition that we have had the great pleasure to witness throughout the week said Colm McLoughlin, Executive Vice Chairman and CEO of Dubai Duty Free. "I mean, I still can not believe it", she said. "The whole tournament I was pretty (much) fighting with my serve". Congrats to Petra, she played an fantastic tournament. "I'm proud of how I managed to play the final".
The world fourth-ranked Czech, with 26 career titles, earned two breaks of her own in the second set, with Hsieh saving a set point in the penultimate game before the contest was levelled at a set apiece.
"She played great, it was a tough one today for sure", Kvitova said.
The affable Swiss joined the WTA Insider Podcast after her win to reflect on her week in Dubai and how she plans to keep her feet on the ground after a statement win.
Bencic broke in the third and seventh games.
It took Kvitova to go off the boil just briefly, first a smash into the net, then a double fault, and she faced three break points.
"Physically I feel great, though I need to take some rest", said the victor whose last four matches all went to three sets. I think people are very surprised about this, but I think the first match against Lucie Hradecka was the most important because, of course, the first round it is never easy and I had some set points against me.
'I think definitely I served much, much better in Melbourne than here. I'm glad that I was able to came back in the second. "It's very hard. Yeah, just very proud of that", she said.
Then Kvitova fought vigorously in the 2nd set to clinch a 4-0 lead before winning 6-1. "And I hope we raise up each other". I had the chances to take few games.