World’s first baby born via uterus transplant from deceased donor

Baby born after womb transplant from dead donor

First baby born following uterus transplant from deceased donor: case study

In this case the 61 year old donor was alive and well at the time, generously giving up her uterus for the cutting-edge operation.

The transplant womb was taken from a mother-of-three who had died from bleeding on the brain.

The healthy baby girl was delivered last December to a 32-year-old woman who wasn't born with a uterus.

The female baby was delivered via Caesarean section at a hospital in Sao Paulo, Brazil, in December 2017 when the mother was nearly 36 weeks pregnant, the study said.

While womb transplants from living donors have been successful, womb transplants from deceased donors still need to be researched, as none of the deceased donor transplants has until now resulted in conception and birth.

She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimised. Scientists have so far reported a total of 39 procedures of this kind, resulting in 11 live births.

In 2016, doctors at the Cleveland Clinic in OH transplanted a uterus from a deceased donor, but it failed after an infection developed. Flyckt and her colleagues in Cleveland have also performed two transplants from deceased donors. And unlike most organ transplants, a donated uterus can be safely removed after a successful pregnancy, allowing the woman to cease taking anti-rejection medication.

He said live uterus donors are rare and typically eligible family members or close friends of women seeking the transplant.

Besides saving the life of patients with failed vital organs, scientists have also conducted hand or face transplants in recent years to improve a person's quality of life.

Doctor Andraus (far left) was the head transplant surgeon involved in the surgery to transplant the donated uterus.

The woman got pregnant via in vitro fertilization (IVF) about seven months after the transplant procedure. After seven months, the fertilised eggs were implanted. Previously, with live donors, doctors have waited at least a year following the transplant to begin trying for a pregnancy.

Study authors wrote that, "the success expands prospects for childbirth among women with infertility attributable to uterine factors".

Both-mother and the baby were discharged three days after birth.

Dr Dani Ejzenberg, from the Faculty of Medicine at Sao Paulo University, who led the team, said: "The use of deceased donors could greatly broaden access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility".

Doctors said in the study that the woman felt "fulfilled" by the chance to carry and deliver her own daughter in spite of her condition.

The researchers said that they were able to implant the fertilised eggs into the transplant uterus much earlier than previous uterus transplants.

It's hard to say definitively whether this shorter wait time made a difference, but the courses of antirejection drugs and antibiotics potentially pose all sorts of complications for the body that just might sway the odds for a developing embryo. At the age of 7 months and 20 days, the baby continued to breastfeed and weighed 15 pounds, 14 ounces.

India vs Australia, 1st Test, Day 1
Sarri says Chelsea loss hurts more thanks to Man City