Ms Abrams, a Yale-educated lawyer who served a decade in the Georgia Legislature, would be the first black female governor in American history. "I mean, this is the South. People have been really wonderful and really optimistic about Stacey Abrams". "I think that's what you are hearing from Oprah".
She said: "Oprah Winfrey has inspired so many of us through the years with her unparalleled ability to form real connections and strengthen the bonds of family and community".
Pence was speaking at a campaign event for Republican Georgia gubernatorial candidate Brian Kemp.
The chat show host appeared on stage to support Democrat Stacey Abrams' campaign to become Governor of Georgia.
Speculation that Winfrey may pursue a White House run against President Donald Trump has been swirling since January, when she delivered a powerful speech at the Golden Globes.
On "Outnumbered", Washington Post editor and Fox News contributor Charlie Hurt said Winfrey is an "entity unto herself", and her endorsement may carry some weight, but he believes Hollywood elites won't swing races for Democrats in next week's midterm elections.
"I am proud to stand with Brian Kemp as our next governor", Walker said in a statement.
"I was sitting at home in California, minding my own business, but I could not stop hearing about what's going on down here", Winfrey said, charming the crowd that had gathered to see her. "Come on, Oprah! It's dehumanizing, it's completely baseless, it's totally cruel, and again I say, you're much better than that and you're much bigger than that".
When a woman opens the door, she lets out an excited cry.
"Stacey Abrams is being bankrolled by Hollywood liberals", Mr Pence said. They don't help. Just ask Hillary Clinton.
More than 1.5 million of the state's nearly 7 million registered voters have cast ballots already. Actor Michael B. Jordan has knocked on doors in Atlanta urging black voters to turn out, and Actor and comedian Will Ferrell has also canvassed for Abrams' campaign.
A pro-Kemp ad funded by the Georgia Republican Party accuses Abrams of trying to allow illegal immigrants to vote.