"As long as I can't see my husband in front of me, speaking to me, I can't have any confidence", Grace Meng was quoted as saying by French TV stations and Sunday newspapers.
Meng Hongwei, a senior Communist Party official, former national security chief and China's first-ever chief of Interpol, has been disappeared inside his country and Interpol has no idea what has happened. China has been known to carry out such detentions for years.
The global police agency Interpol announced Sunday that its missing president had resigned "with immediate effect" after China said the man was under investigation over unspecified legal violations and his wife told reporters that he had texted her an image of a knife, leading her to believe he was in danger.
The paper, which based its reporting on an unnamed source, said the reason for Meng's questioning was unknown. He was the first Chinese national to hold the position, which he was appointed to in 2016.
France launched its own investigation, with French authorities saying Meng boarded a plane and arrived in China, where the trail goes cold. The one-sentence announcement about his being the focus of an investigation, issued when it was almost midnight in China, said only that Meng was in the custody of party investigators.
Beijing, which had remained tight-lipped about Meng's fate since French officials disclosed his disappearance on Friday, said in a one-line statement that Meng "is now under investigation on suspicion of violating the law".
Asked if she believed that he has been arrested, she said: 'In China, what happened, I'm not sure'.
"This is political ruin and fall!" she wrote in a text message to the AP.
China's top anti-corruption agency said in a one-sentence statement Sunday that Meng was suspected of breaking the law, without giving details.
She said she was taking the unusual step of speaking out because she felt a greater responsibility. Some of them might even have been pursued by Chinese authorities under Meng's watch. She told police that she last heard from him 10 days prior and had received threats on social media and by telephone, according to the statement.
But the call never came, she said, adding that she did not what happened to her husband. She said he was in China when he sent the image. "After that I have no call and he disappeared". Normally, they would be in daily contact when he was away working, she said.
Interpol has said it is concerned about his apparent disappearance and has made inquiries with China. She said he was in China when he sent the message.
Interpol said it had received his resignation on Sunday with immediate effect. The matter belongs to the worldwide community. Meanwhile, Interpol has announced plans to elect a new president next month, apparently unconcerned about the fate of its last one.
She issued an emotional plea for worldwide help to find her husband.
That indicates Meng has been caught up in the broad anti-corruption campaign ordered by President Xi Jinping, and which has already led to the disappearance of many senior figures.