It turned out Brandon's mum, who had kept hold of a photo of Vilma holding her son, had asked him to keep an eye out for the nurse when he began his residency, but he simply assumed she would have retired by now.
Wong, 54, told The Mercury News she saw someone visiting with patients who had not checked in at the nurse station.
"He told me that. he was a premature baby born at our hospital. I then got very suspicious because I remember being the primary nurse to a baby with the same last name", she added.
Wong recalled his father was a police officer and asked him if he was the same person.
Vilma said she was initially in shock about the meeting, "But overjoyed to know that I took care of him nearly 30 years ago and now he's a paediatric resident to the same population he was part of when he was born".
Seminatore was stunned Wong remembered caring for him 28 years ago - out of the tens of thousands of kids who have passed through the unit since then.
Ms Wong and fellow nurse Kas Pilon are legendary in his family for their kindness and tender care, newspaper reported. For him, meeting Wong was a "surreal experience".
Almost three decades ago, there was a preemie with the same name that Wong had cared for in the NICU.
Mr Seminatore (pictured with Ms Wong) weighed two pounds and six ounces when he was born in 1990.
When Seminatore's mom heard he was doing a month-long rotation in the NICU, she urged him to ask about both women. "They helped calm a lot of our fears".
"They were the most wonderful nurses, " his mother, Laura Seminatore, told the Mercury News.
Wong's curiosity grew, so at one point she just asked Seminatore.
Wong remembered the Seminatore baby's father was a police officer. By that time, he was able to eat on his own and was beginning to thrive, Wong remembered.
The story of their reunion at Lucile Packard Children's Hospital in Palo Alto has gone viral on social media. He's now grown up and works in the same hospital he was born in. Brandon, one of our pediatric residents, was born 28 years ago in our NICU-then just 29 weeks old. She considers meeting Dr Seminatore for the second time the pay-off of her mission.
But last month, she saw a young Intern made a decision to find out who he is, Vilma told the Mercury News.
Hospital Lucile Packard Children's Hospital chose to publish on his page in Facebook unique story of the reunification of Wilma and Brandon.