'Medics from ER24 and other services are at the scene of a plane crash at Wonderboom in Pretoria, ' Russell Meiring, spokesman for the ER24 medical service, said.
Images showed a burning aircraft marked "Martin's Air Charter".
The remains of a charter aircraft that crashed near Wonderboom Airport, north of Pretoria.
The large plane appeared to have crashed through a nearby building, the official said. Reports say that there have been no deaths but there are 20 people injured.
"There was one fatality in the cockpit, we are not sure if it's the pilot or the engineer".
A plane has crashed near the Wonderboom airport in Pretoria, South Africa.
"There are critical patients‚" Loubser said.
Russel Meiring of ER24 said at least 20 people were hurt.
The plane had been due to fly later this week to Aviodrome via east Africa, through Egypt, Croatia, Austria to the Netherlands.
Civil Aviation Authority spokesman Kabelo Ledwaba said its investigators were at the scene and would issue a statement.
"ER24 paramedics, along with several other services, are now on the scene treating and triaging the patients", the emergency services group said in a statement on Tuesday.