But on Wednesday, she took a softer stance, coming to Gilbert's defense after one of her followers sent a critical tweet.
Barr declared that she was going to leave Twitter on Tuesday morning, only to return in the evening with a late-night tweet storm that blamed her original offending tweet on Ambien, and then called out several of her co-stars for throwing her "under the bus".
At a press briefing at the White House Wednesday, Sanders said Trump was "simply calling out the media bias" in his tweet about Iger.
She also noted that the experience was helping her to "move in2 a better place" that would allow her the opportunity to "help suffering people who are homeless battered & hopeless in this world".
"One stupid joke in a lifetime of fighting 4 civil rights 4 all minorities, against networks, studios, at the expense of my nervous system/family/wealth will NEVER b taken from me". Hours later, however, Barr was back on social media, lashing out at colleagues sharing their views on her racially charged comment.
A since-deleted tweet blaming her outburst on a dose of the sleeping pill Ambien, prompted a swift retort from pharma giant Sanofi.
She added: "Guys I did something unforgiveable so do not defend me".
Was ABC's gamble worth the risk to its reputation?
ABC is cancelling Roseanne, and it comes at a big price. "But before it did the right thing, it did the wrong thing", she wrote.
For instance, just before tweeting her apology for her tweet about Jarrett and announcing that she was once again taking a break from Twitter, Barr retweeted a recommendation for a website dedicated to the QAnon conspiracy theory. Other members of the "Roseanne" cast haven't been as circumspect as Goodman. The network - indeed all of broadcast television - needed some successful comedies.
President Trump has since chimed in on Twitter - not exactly defending Barr, but rather complaining about his own treatment. "I don't know anything about it", Goodman said when asked what his response was to the fallout. She called it "abhorrent, repugnant and inconsistent with our values".
She also said she felt bad for Trump because "he goes thru this every single day".
Barr has previously apologised to Ms Jarrett, writing: "I want to apologize to you".
Jarrett, who said she was "fine" after the slur, urged in an MSNBC special Tuesday about racism that the incident become a teaching moment.
Both former executives praised ABC for moving swiftly when presented with Barr's tweet.
"Roseanne wasn't a top five or top 10 show, it was the top show on ABC".