The 23-year-old is now enjoying his most prolific goalscoring season as a top-flight footballer, having registered 23 goals while creating a further 12 across 45 matches in all competitions, and Guardiola has made his feelings about his long-term future clear.
"There are so many (special moments). the 18 games won in a row is the reason we have won the league".
Meanwhile, Guardiola predicts a low-key summer of transfer activity, with veteran midfielder Yaya Toure the only player who is confirmed as a definite departure.
"Maybe I will be concerned by that and maybe they will be in the line-up, maybe they will play".
"Now we are going to change some details". One or maybe two.
But the Spaniard admits there are no guarantees Aguero will not leave because what the club's all-time leading scorer does next is up to him.
"It's happened many times in these press conferences and I said maybe a thousand times Sergio is going to stay until he decides, "My time here is over".
Aguero bagged 30 goals as City clinched the English Premier League title and lifted the Carabao Cup.
"We want him to stay as long as possible".
He was equally effusive about the impact new signing Bernardo Silva has had after joining from Monaco last summer. The Red Devils have had more games shown on TV this term - 28 times, which is same as Arsenal - compared to City's 25, by broadcasters Sky Sports and BT Sport.
"I said not too much [will change] but it depends on the players", he said. We're going to try for 100 points and finish this nearly ideal season in the Premier League.
"As long as I am a coach at Manchester City, he isn't going anywhere".
He said: "I say not too many because we had a high investment last season". With the forward set to be named in Gareth Southgate's England World Cup squad, talks may not resume before July.