Winfrey, when asked backstage if she planned to run for president, replied, "I don't".
"I also know that after years of watching The Oprah [Winfrey] Show you always have the right to change your mind". Other celebrities started talking about a possible President Winfrey, with actress Meryl Streep telling The Washington Post that she would endorse the 63-year-old TV personality on a Presidential ticket.
Winfrey delivered a powerful speech during Sunday night's Golden Globes after earning a lifetime achievement award, prompting several calls around the country for her to a mull a presidential bid in 2020. But the television star never did anything like that.
Oprah has raised millions of dollars for various causes, including shelters for battered women but, like Mr Trump when he launched his White House campaign, she has no prior experience in government. "Oprah will be lots of fun", Trump told reporters during a meeting with lawmakers about immigration.
"No, I absolutely don't think that her position has changed".
Trump on Monday, speaking to a national convention of farmers in Tennessee, did not mention Winfrey's name or make any reference to his re-election campaign.
"To the media, the left in this country, Oprah apparently is their chosen one, she's the new messiah that they'll blindly worship and follow like the sheep they are", Hannity said. 'I don't think she is actively considering it at this time'.
Barbara Streisand accepting her award
Even so, for Democrats in early voting states, and perhaps for a public that largely disapproves of President Donald Trump's job performance, the notion of a popular media figure as a presidential candidate is not as odd as it once seemed, given the NY real estate mogul and reality TV star now in the White House.
During a 2008 rally for the candidate, Winfrey said she was "not here for partisan beliefs" and that over the years, she'd voted for as many Republicans as she had Democrats. "At the same time, politics is ridiculous right now". The chat show host talked powerfully about the moments that had inspired her as a little girl before tackling racism, sexism, the Hollywood sexual harassment scandal and the wider implications for ordinary women. "But now she doesn't have a choice", said Streep.
"People need to have hope", said Ray Buckley, chairman of the New Hampshire Democratic Party, who encouraged the idea of an Oprah run.
"So I want, tonight, to express gratitude to all the women who have endured years of abuse and assault because they, like my mother, had children to feed and bills to pay and dreams to pursue". Let's all come together, women & men, & say #TIMESUP! He's got a job approval of 54 percent and disapproval of 30 percent.
Winfrey, in September and October, publicly dismissed the notion of seeking the nation's highest office, though she noted that Trump's victory made her rethink the requirements of the office. She has been poor & now rich. Oprah stood up at the Golden Globes and said, not this time.
Late-night show host Jimmy Kimmel said Monday that he preferred Winfrey to Trump.