He now feels confident that Tottenham will resist any more major players leaving, and believes they are staying on course for sustained success.
Argentine Pochettino is unbeaten in six Premier League meetings with Wenger's Arsenal since arriving from Southampton in 2014, and last season Tottenham finished above Arsenal in the league for the first time in 22 years.
It's a bold prediciton seeing as Arsenal are the bookies' favourite for the match and are at home. That used to be the case at Arsenal, but no more.
"No, not at all", he said, when asked if he thought Arsenal will be the underdog on Saturday.
"Not at all.I think Tottenham is a good side but we have the quality to win this game and that is what we want to show".
The 26-year-old made something of a mockery of Wenger's decision by scoring just nine minutes after his second half introduction to briefly bring his side back into a contest which was eventually settled when Gabriel Jesus put City 3-1 ahead with a contentious goal.
Arsene Wenger insists Arsenal are not the underdogs ahead of north London derby against Tottenham
It means the manager, who has not lost a league game against Arsene Wenger in his three years at the helm, will have to decide whether to give youngster Harry Winks a starting place in place of the more experienced Mousa Dembele and whether Danny Rose has done enough to push Ben Davies out of the side.
And Wenger says Arsenal will have to assess the situation on Monday.
"It is a massive challenge to.be competitive against a team that in last 20 years won more trophies than us".
He added, "Two years ago when we finished above them we were disappointed because we didn't win the title".
Kane has scored in his last five games against Arsenal.
"But Harry Kane, Dele Alli and Christian Eriksen are not going anywhere in a hurry and they are moving into a new stadium in order to compete".
Lacazette became Arsenal's club-record signing in the summer after arriving from Lyon, and has started all but two Premier League games.